'Toon star Roger is worried that his wife Jessica is playing pattycake with someone else, so the studio hires detective Eddie Valiant to snoop on her. But the stakes are quickly raised when Marvin Acme is found dead and Roger is the prime suspect. Groundbreaking interaction between the live and animated characters, and lots of references to classic animation.

A legendary dog trainer believes he can transform Marmaduke from an undisciplined, but lovable dog, into the first Great Dane to win the World Dog Championship.

Some time after the Mousekewitz's have settled in America, they find that they are still having problems with the threat of cats. That makes them eager to try another home out in the west, where they are promised that mice and cats live in peace. Unfortunately, the one making this claim is an oily con artist named Cat R. Waul who is intent on his own sinister plan. Unaware of this, the Mousekewitz's begin their journey west, while their true cat friend, Tiger, follows intent on following his...

Captain New Eyes travels back in time and feeds dinosaurs his Brain Grain cereal, which makes them intelligent and non-violent. They agree to go to the Middle Future (our era) in order to grant the wishes of children in New York city. They are to meet Dr. Bleeb of the Museum of Natural History, but get sidetracked with their new children friends and run into the Captain's evil brother, Professor Screw Eyes, who has other plans for the dinosaurs.